Eugene Braunwald was born in Vienna, Austria in 1929 and moved to the United States in 1939. He received BA and MD (Honor) from New York University, and completed his residency in Cardiology at Johns Hopkins University. In 1968, he joined the University of California at San Diego where he founded the Department of Medicine and served as Chief of Cardiology and Clinical Director at the National Heart, Lung and Blood Institute. From 1972 to 1996 he chaired the Department of Medicine at Brigham and Women’s Hospital in Boston, MA. He was the President of the American Society for Clinical Investigations and the Association of Professors of Medicine. He is currently Distinguished Heresy Professor of Medicine at Harvard University and Faculty Dean for Academic Programs at Brigham and Women’s Hospital and Massachusetts General Hospital in Boston and Academic Head of the Partners in Health Care System.
Professor Braunwald is at the forefront of investigators of congestive heart failure and acute coronary syndromes. Over the past 40 years, he conducted pioneering research on the hemodynamic response to surgical correction of valvular disorders; he also developed pioneering diagnostic techniques and discovered the clinical entity of idiopathic, hypertrophic subacute stenosis. His groundbreaking studies on the role of the autonomous nervous system and its mediators in the physiologic adjustments to heart failure and the mechanisms of contraction of the normal and failing heart had profoundly influenced present knowledge of the pathophysiology of congestive heart failure. Braunwald also made seminal contributions to the treatment of heart failure, leading to large-scale clinical trials that altered treatment strategies worldwide. He was also instrumental in running the “Thrombolysis in Myocardial Infarction” studies, which developed the concepts of thrombosis superimposed on atherosclerosis as the pathological bases for acute myocardial infarction.
Professor Braunwald published more than 1200 scientific papers and around 20 books. His work dramatically expanded knowledge of heart disease in the areas of congestive heart failure, coronary artery disease, and valvular heart disease. He is the founding editor of the premier cardiology textbook, Braunwald’s Heart Disease, which is now in its 7th edition, and has been editor-in-chief of the leading textbook Harrison’s Principles of Internal Medicine and is still one of its co-editors. He is also Editor-in-Chief of MD Consult Cardiology. In addition to the King Faisal International Prize for Medicine, Professor Braunwald received countless awards and honors, including ten honorary doctorate degrees, the latest from the University of Rochester in 2010. He is an Honorary Fellow of the Royal College of Physicians in Britain and the American College of Chest Physicians and the only cardiologist who is a member of the National Academy of Sciences, In 1996, Harvard University incepted the Eugene Braunwald Professorship in Medicine as a permanently endowed chair, and in 1999 the American Heart Association incepted the annual Eugene Braunwald Academic Mentorship Award in his honor.
Professor Eugene Braunwald, has been awarded the prize. He has had a long and distinguished career over the past 40 years and has been at the forefront of the investigation of congestive heart failure and the acute coronary syndromes. He contributed to more than 1100 publications and is the editor of a textbook of cardiovascular medicine that has been highly successful and editor of Harrison’s Principles of Internal Medicine. Professor Braunwald and his colleagues explored, identified and established the role of the sympathetic nervous system in congestive heart failure. They developed a novel model in animals for congestive heart failure that has been used by many Laboratories to evaluate pathophysiologic studies and effects of therapy. Professor Braunwald was amongst the first to delineate the importance of idiopathic hypertrophic subaortic stenosis and the physiologic abnormalities of this myopathic process. He and Robert Kioner were the first to develop the concept of post- Ischaemic left ventricular dysfunction after temporary reduction and coronary flow. This key concept relating to reversible left ventricular dysfunction, its causes, consequence and opportunities for modulation remains a contemporaneously important issue.